Research

While training at Cooper University Hospital, fellows are given an opportunity to participate in clinical and basic translation research. With the help of faculty mentors, fellows develop IRB proposals, and write grants and manuscripts for publication. There are vast resources which are available to facilitate scholarly pursuits.

Cooper Research Institute

Through basic and clinical research, faculty at Cooper University Hospital are bringing scientific discoveries to life with access to cutting-edge treatments in fields such as oncology, cardiology, critical care, diabetes, and gene therapy. Cooper faculty members currently conduct over 400 National Institutes of Health (NIH) and industry-sponsored clinical trials each year. In South Jersey, many of these are only available at Cooper. The campus now holds about 46 NIH and federal grants and nearly $30,000,000 in aggregate research funding, making it number one among the regional medical campuses in the country. Past research by Cooper faculty has led to new standards of care and novel therapies in fields such as oncology, cardiology, surgery and orthopaedics.

Coriell Institute of Medical Research

The Coriell Institute for Medical Research is an independent, not-for-profit research organization dedicated to understanding human genetic diseases and providing the highest quality genetic resources. Its affiliation with Cooper University Hospital provides an excellent opportunity to our residents to participate in a variety of basic science research.

Recent Interventional Pulmonary Scholarly Activity

 

Abouzgheib W, Abramian O, Ren S, Rafferty W, Patel B, Madisi N, Kannarkatt P, Lowa K, Hunter K, Boujaoude Z. Quality of transbronchial biopsy with large forceps compared to cryobiopsy: a randomized controlled, single blinded live animal study. J Thorac Dis. 2022 Apr;14(4):1079-1087. doi: 10.21037/jtd-21-936. PMID: 35572896; PMCID: PMC9096277.

Kubicek GJ, Khrizman P, Squillante C, Callahan K, Xu Q, Abouzgheib W, Boujaoude Z, Patel A, Hageboutros A. Stereotactic Body Radiotherapy and Systemic Dose Chemotherapy for Locally Advanced Lung Cancer: Single Arm Phase 2 Study. Am J Clin Oncol. 2022 Mar 1;45(3):129-133. doi: 10.1097/COC.0000000000000892. PMID: 35195562.

Green A, Puri N, Kouch M, Wolfe Y, Balakrishnan A, Abramian O, Boujaoude Z, Abouzgheib W. Cryotherapy: A Safe Approach to Pulmonary Hemorrhage During VV-ECMO. J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221074590. doi: 10.1177/23247096221074590. PMID: 35152803; PMCID: PMC8848090.

Abramian O, Rosenheck J, Taddeo-Kolman D, Bowen F, Boujaoude Z, Abouzgheib W. Therapeutic closure of bronchopleural fistulas using ethanol. Ther Adv Respir Dis. 2021 Jan-Dec;15:17534666211044411. doi: 10.1177/17534666211044411. PMID: 34494916; PMCID: PMC8438938.

Gaspard D, Boujaoude Z, Kubicek G, Abouzgheib W. Transthoracic placement of fiducials with ultrasound or electronic navigational bronchoscopy needle guidance by the interventional pulmonologist: A case series. Respirol Case Rep. 2021 Jul 29;9(9):e0818. doi: 10.1002/rcr2.818. PMID: 34336221; PMCID: PMC8319654.

Ziad Boujaoude, Nagendra Madisi, Bhavi Patel, Jean-Sebastien Rachoin, R. Phillip Dellinger, Wissam Abouzgheib, "Safety and Feasibility of a Novel Protocol for Percutaneous Dilatational Tracheostomy in Patients with Respiratory Failure due to COVID-19 Infection: A Single Center Experience", Pulmonary Medicine, vol. 2021, Article ID 8815925, 5 pages, 2021. https://doi.org/10.1155/2021/8815925

Kubicek, Greg, Khrizman, Polina, Squillante, Christian, Xu, Qianyi, Abouzgheib, Wissam, Boujaoude, Ziad, Patel, Ashish, Hageboutros, Alexandre.  Stereotactic body radiotherapy and systemic dose chemotherapy for locally advanced lung cancer, single-arm phase II study. J Clin Oncol. 2020;38(15):e21081. doi:10.1200/JCO.2020.38.15_suppl.e21081.

Rohan Arya, Ziad Boujaoude, William J. Rafferty & Wissam Abouzgheib (2020) Usefulness and safety of transbronchial biopsy with large forceps during flexible bronchoscopy, Baylor University Medical Center Proceedings, DOI: 10.1080/08998280.2020.1835123

Madisi NY, Abouzgheib W, Bowen F, Boujaoude Z. Inferior Vena-cava Filter fracture embolization to the left lung complicated by Massive Hemoptysis [published online ahead of print, 2020 Mar 30]. Ann Thorac Surg. 2020;S0003-4975(20)30429-X. doi:10.1016/j.athoracsur.2020.02.054

Borah A, Cocciardi S, Boujaoude Z, Abouzgheib W. Erroneous bronchial transection after video assisted thoracoscopic surgery (VATS) pulmonary resection diagnosed with bronchoscopy: Case report. Medicine (Baltimore). 2019 Dec;98(50):e18377. doi: 10.1097/MD.0000000000018377. PubMed PMID: 31852149.

Cocciardi S, Borah A, Terrigno R, Abouzgheib W, Boujaoude Z. A case report of an expensive yet necessary thoracentesis: Expanding the boundaries of endoscopic ultrasound transbronchial needle aspiration. Medicine (Baltimore). 2019 Oct;98(41):e17555. doi: 10.1097/MD.0000000000017555. PubMed PMID: 31593139.

Abouzgheib W, Ben-Jacob T, Borah A, Terrigno R, Cruz-Morel K, Dy R, Gratz I, Boujaoude Z: A Randomized Controlled Trial Comparing a Mapleson Circuit with Nasal Trumpet to Standard Oxygen Supplementation during EBUS Bronchoscopy under Monitored Anesthesia Care. Biomed Hub 2019;4:1-9. doi: 10.1159/000502110

Boujaoude Z, Arya R, Shrivastava A,Pratter M, Abouzgheib W, “Impact of Moderate Sedation versus Monitored Anesthesia Care on Outcomes and Cost of Endobronchial Ultrasound Transbronchial Needle Aspiration,” Pulmonary Medicine, vol. 2019, Article ID 4347852, 6 pages, 2019.

Patel B, Abi-Fadel D, Rosenheck J, Bartter T, Boujaoude Z, Abouzgheib W. Endobronchial Valves for Treatment of Hemoptysis. J Bronchology Interv Pulmonol. 2019 Apr;26(2):e22-e24.

Abouzgheib W, Arya R, Cruz-Morel K, Koleman D, Kass J, Boujaoude Z, DelGiacco E, Bartter T. The Impact of Continuous Positive Airway Pressure upon Pleural Fluid Pressures during Thoracentesis. Respiration. 2019 Apr 17:1-5

Peterson J, Niles C, Patel A, Boujaoude Z, Abouzgheib W, Goldsmith B, Asbell S, Xu Q, Khrizman P, Kubicek GJ. Stereotactic Body Radiotherapy for Large (> 5 cm) Non-Small-Cell Lung Cancer. Clin Lung Cancer. Clin Lung Cancer. 2017 Jul;18(4):396-400. doi: 10.1016/j.cllc.2016.11.020.

Gaspard D, Bartter T, Boujaoude Z, Raja H, Arya R, Meena N, Abouzgheib W. Endobronchial valves for bronchopleural fistula: pitfalls and principles. Ther Adv Respir Dis. 2017 Jan;11(1):3-8. doi: 10.1177/1753465816672132. Epub 2016 Oct 15.

Meena N, Abouzgheib W, Patolia S, Rosenheck J, Boujaoude Z, Bartter T. EBUS-TBNA and EUS-FNA: Risk Assessment for Patients Receiving Clopidogrel. J Bronchology Interv Pulmonol  2016 october ;22(3):237-43

Nikhil Meena; Wissam Abouzgheib; Ziad Aboujaoude; Thaddeus Bartter. Endosonography Endoscopic Ultrasound Is Superior: Esophagus Is Better! Chest. 2015;148(4):e129. doi:10.1378/chest.15-1262

Boujaoude Z, Bartter T, Abboud  M, Pratter M, Abouzgheib WPleuroscopic Pleurodesis Combined With Tunneled Pleural Catheter for Management of Malignant Pleural Effusion: A Prospective Observational Study  J Bronchology Interv Pulmonol. 2015 Jul;22(3);237-24

Gaspard D, Raja H, Arya R, Abouzgheib W, Boujaoude Z. A case report on the diagnosis of a rare pleural tumor with endobronchial ultrasound: breaking new boundaries. Medicine (Baltimore). 2015 Mar;94(10):e561

Arya R, Boujaoude Z, Gratz I, Akers S, Abouzgheib W. Bronchial stenosis secondary to epidermolysis bullosa successfully treated with bronchoscopic balloon dilatation. Respirol Case Rep. 2015 Mar;3(1):33-5

Perwaiz M, Boujaoude Z, Ranasuriya G, Raja H, Gaspard D, Abouzgheib W. Primary pulmonary choriocarcinoma: a diagnostic dilemma. J Bronchology Interv Pulmonol. 2015 Apr;22(2):183

Ranasuriya G, Mian A, Boujaoude Z, Tsigrelis C. Pulmonary toxocariasis: a case report and literature review. Infection. 2014 Jun;42(3):575-8

Boujaoude Z, Pratter M, Abouzgheib W. Transpulmonary artery needle aspiration of hilar masses with endobronchial ultrasound: a necessary evil. J Bronchology Interv Pulmonol. 2013 Oct;20(4):349-51

Abouzgheib W, Meena N, Jagtap P, Schorr C, Boujaoude Z, Bartter T. Percutaneous dilatational tracheostomy in patients receiving antiplatelet therapy: is it safe? J Bronchology Interv Pulmonol. 2013 Oct;20(4):322-5.

Pedro Dammert, Ziad Boujaoude, William Rafferty, Jonathan Kass. Fever of unknown origin and pancytopenia caused by culture-proven delayed onset disseminated bacillus Calmette-Guérin (BCG) infection after intravesical instillation  BMJ Case Reports 2013; doi:10.1136/bcr-2013-008949

Boujaoude Z, Arya R, Rafferty W, Dammert P. Organising pneumonia in common variable immunodeficiency. BMJ Case Rep. 2013 Jun 7;2013. doi:pii: bcr2013008905. 10.1136/bcr-2013-008905.

Boujaoude Z, Young D, Lotano R, Abouzgheib W. Cryosurgery for the immediate treatment of acute central airway obstruction J Bronchology Interv Pulmonol. 2013 Jan;20(1):45-7.

Dammert P, Pratter M, Boujaoude Z. Safety of ultrasound-guided small-bore chest tube insertion in patients on clopidogrel.J Bronchology Interv Pulmonol. 2013 Jan;20(1):16-20

Boujaoude, Ziad; Raja, Haroon; Dammert, Pedro; Aortobronchial Fistula Successfully Treated with TEVAR . BMJ Case Reports 2012; doi:10.1136/bcr.01.2012.5622

Boujaoude Z, Malin J, Abouzgheib W. Hodgkin Disease of the Trachea. J Bronchology Interv Pulmonol. 2012 Jul;19(3):200-2.

Abouzgheib W, Gaspard D, Boujaoude Z. Migrating tumor: a serious complication of use of endobronchial snare loop.J Bronchology Interv Pulmonol. 2012 Jul;19(3):262-3

Boujaoude, Ziad; Dahdel, Maher; Pratter, Melvin ; Kass, Jonathan : Endobronchial Ultrasound With Transbronchial Needle Aspiration in the Diagnosis of Bilateral Hilar and Mediastinal Lymphadenopathy.: J Bronchology Interv Pulmonol 2012 ; Volume 19, issue 1: 19–23