July 2024 to June 2025
- T. Hess, MD (General Surgery Resident)
- Comparison of robot-assisted versus laparoscopic repair of perforated gastroduodenal ulcers [under review]:
Abstract submitted for presentation at AAST 2025, September 10-13, 2025, Boston, MA. - Chemotherapy versus targeted therapy in high and low NRF2 lung adenocarcinoma: Histological transformation is key [under review]:
Abstract submitted for presentation at ASCO 2025, May 30-June 3, 2025, in Chicago, IL. - NRF2 activity impairs the efficacy of Sotorasib in human KRAS-mutant lung adenocarcinoma:
Abstract selected for presentation at the AACR Annual Meeting 2025, April 25-30, 2025, in Chicago, IL. - Fast MRI for pediatric appendicitis can adequately diagnose female gynecologic pathology [under review]:
Abstract submitted for presentation at the ACS 2025, April 5-8, 2025, Washington, DC. - NRF2 activity impairs the efficacy of Sotorasib in human KRAS-mutant lung adenocarcinoma:
Abstract selected for a podium presentation at the SSO Annual Meeting 2025, March 27-29, 2025, in Tampa, FL.
- Comparison of robot-assisted versus laparoscopic repair of perforated gastroduodenal ulcers [under review]:
- Rachel Nation (General Surgery Resident)
- Lighting Up PNET: Creating a Murine Model with a Novel Bioluminescent Cell Line:
Abstract selected for an e-poster presentation at the SSO Annual Meeting 2025, March 27-29, 2025, in Tampa, FL. - Lighting Up PNET: Creating a Murine Model with a Novel Bioluminescent Cell Line:
Abstract selected for a Quick Shot presentation at the Philadelphia Academy of Surgery, February 3, 2025.
- Lighting Up PNET: Creating a Murine Model with a Novel Bioluminescent Cell Line:
- Hannah Sofield, MD (General Surgery Resident)
- Targeting MET Activation in CDH1 Deficient Diffuse Gastric Cancer with Peritoneal Metastases [under review] &
Location Based Outcomes in Neoadjuvant vs. Adjuvant Systemic Therapy In Small Bowel Adenocarcinoma [under review]:
Abstract submitted for presentation at the ACS 2025, April 5-8, 2025, Washington, DC. - Targeting MET activation in CDH1 deficient diffuse gastric cancer with peritoneal metastases: Abstract selected for presentation at the AACR Annual Meeting 2025, April 25-30, 2025, in Chicago, Il.
- Treatment Patterns of Anal Melanoma in the Era of Immunotherapy:
Abstract selected for an e-poster presentation at the SSO Annual Meeting 2025, March 27-29, 2025, in Tampa, FL. - Targeting MET activation in CDH1 deficient diffuse gastric cancer with peritoneal metastases:
Abstract selected for a Quick Shot presentation at the Philadelphia Academy of Surgery, February 3, 2025. - Second author and mentor to 3 medical students regarding their below abstract/poster submissions for the Camden Scholars Forum 2025:
- Induction of Arterial Thrombosis in a High-Risk Patient by Pre-Operative Cessation of Antiplatelet Therapy
- Hirschsprung's Associated Enterocolitis Following Laparoscopic-Assisted Soave Pull-Through Procedure
- Diagnosis of Bilateral Adrenal Masses
- Targeting MET Activation in CDH1 Deficient Diffuse Gastric Cancer with Peritoneal Metastases [under review] &
- Gena Topper, MD (General Surgery Resident)
- Epigenetic Agents Romidepsin and Mithramycin Show Major Promise In Vitro As Intraperitoneal Chemotherapy Perfusion Agents for Peritoneal Colorectal Cancer [under review]:
ACS 2025, April 5-8, 2025, Washington, DC. - A Novel Peritoneal Carcinomatosis Murine Model For Intraperitoneal Epigenetic Chemotherapy:
Abstract selected for oral presentation at the 20th Annual Academic Surgical Congress, February 11-13, 2025 in Las Vegas, NV. - Development of a Preclinical Model to Evaluate Epigenetic Therapies in HIPEC for Colorectal Cancer with Peritoneal Carcinomatosis:
Abstract selected for oral presentation at the Philadelphia Academy of Surgery, February 3, 2025. - Sex Dimorphic Outcomes After Whole Blood Resuscitation in Trauma Patients:
Winner of the American College of Surgeons Regional Trauma Paper Competition, December 6, 2024, Kansas, City, MO, and also the 46th Annual New Jersey Committee of Trauma Paper Competition, November 11, 2024.
- Epigenetic Agents Romidepsin and Mithramycin Show Major Promise In Vitro As Intraperitoneal Chemotherapy Perfusion Agents for Peritoneal Colorectal Cancer [under review]:
- Chelsea Katz, MD (Gyn/Onc Fellow)
- High Grade Serous Ovarian Cancer Differentiation and invasion post-chemotherapy: NRF2 has a role [under review]:
Abstract submitted for presentation at ASCO 2025, May 30-June 3, 2025, in Chicago, IL. - Chemotherapies change the NRF2 levels and impact the differentiation and growth of human high grade serous ovarian cancer:
Abstract selected for presentation at the AACR Annual Meeting 2025, April 25-30, 2025, in Chicago, IL. - Tumor microenvironment in high- versus low-NRF2 high grade serous ovarian cancer and the impact on prognosis:
Abstract selected for poster presentation at the Society of Gynecologic Oncology (SGO) Winter Meeting 2025, January 30-February 1, 2025 in Whistler, British Columbia, Canada.
- High Grade Serous Ovarian Cancer Differentiation and invasion post-chemotherapy: NRF2 has a role [under review]:
- Zachary Ladd, MS (M3 Student)
- Identification of Inhibitors Targeting DLG and ETGE Mutants of NRF2 in Esophageal Squamous Cell Carcinoma:
Abstract selected for oral presentation at the Camden Cancer Center Research Center Retreat, October 4, 2024, Cape May, NJ. - Triamterene and Asinex 1 Inhibit NRF2 Expression in NRF2 Esophageal Squamous Cell Carcinoma:
Abstract selected for presentation at the 20th Annual Academic Surgical Congress, February 11-13, 2025 in Las Vegas, NV. - Abstract selected for presentation at the AACR Annual Meeting 2025, April 25-30, 2025, in Chicago, IL.
- Saleh Z, Verchio V, Ghanem YK, Lou J, Hundley E, Rouhi AD, Joshi H, Moccia MC, Scalia DM, Lenart AM, Ladd Z, Minakata K, Shersher DD. Optimizing outcomes in paraesophageal hernia repair: a novel critical view. Surg Endosc. 2024;38(9):5385-5393. doi:10.1007/s00464-024-11104-2.
- Identification of Inhibitors Targeting DLG and ETGE Mutants of NRF2 in Esophageal Squamous Cell Carcinoma:
July 2023 to June 2024
- Yazid Khalil Mo Ghanem, MD (General Surgery Resident)
- Novel Epigenetic Therapy With Romidepsin And Mithramycin As Intraperitoneal Chemotherapy Perfusion Agents For Peritoneal Colorectal Cancer:
Abstract selected for a Quick Shot Presentation at the ACS Clinical Congress, October 19-22, 2024, San Francisco, CA. - Saleh Z, Verchio V, Ghanem YK, Lou J, Hundley E, Rouhi AD, Joshi H, Moccia MC, Scalia DM, Lenart AM, Ladd Z, Minakata K, Shersher DD. Optimizing outcomes in paraesophageal hernia repair: a novel critical view. Surg Endosc. 2024;38(9):5385-5393. doi:10.1007/s00464-024-11104-2.
- Promising Potential for Mithramycin A, a novel epigenetic antineoplastic agent, in cytoreductive surgery for peritoneal colorectal cancer:
- Abstract (one of only 24) accepted for presentation at the 39th Annual SSAT Residents and Fellows Research Conference, May 18-21, 2024, Washington, DC. Abstract presented at the Plenary Session and at an SSAT Annual Meeting scientific session.
- Improving the Readability of Patient Education Materials About the Whipple Procedure Using Artificial Intelligence, Ghanem YK, Rouhi AD, et al. Accepted for a Mini Oral Presentation at AHPBA 2024, April 4-7, 2024, Miami, FL.
- Use of Novel Epigenetic Therapy Agent Romidepsin in Cytoreductive Surgery for Peritoneal Colorectal Cancer, Ghanem YK et al. Accepted for an ePoster at the Society of Surgical Oncology (SSO) 2024, March 20-23, 2024, Atlanta, GA.
- Novel Epigenetic Therapy With Romidepsin And Mithramycin As Intraperitoneal Chemotherapy Perfusion Agents For Peritoneal Colorectal Cancer:
- Hansa Joshi, MD (General Surgery Resident)
- Transformation From Lung Adenocarcinoma To Squamous Cell Carcinoma: Drug Resistance And The Role Of Nrf2:
Abstract selected for a full oral presentation at the ACS Clinical Congress, October 19-22, 2024, San Francisco, CA. - Saleh Z, Verchio V, Ghanem YK, Lou J, Hundley E, Rouhi AD, Joshi H, Moccia MC, Scalia DM, Lenart AM, Ladd Z, Minakata K, Shersher DD. Optimizing outcomes in paraesophageal hernia repair: a novel critical view. Surg Endosc. 2024;38(9):5385-5393. doi:10.1007/s00464-024-11104-2.
- Transformation from lung adenocarcinoma to squamous cell carcinoma: Drug resistance and the role of NRF2, Presentation, Joshi, Hansa, 1st place winner at the Resident Research Day 2024, June 20, 2024
- Transformation in non-small cell lung cancer subtypes: Drug resistance and the role of NRF2, Poster, Joshi, Hansa, 2nd place winner at the Camden Scholars' Forum 2024, May 2, 2024
- Transformation From Lung Adenocarcinoma To Squamous Cell Carcinoma: Drug Resistance And The Role Of Nrf2:
- Matthew Moccia, MD (General Surgery Resident)
- Development Of A Bioluminescent Murine Neuroendocrine Tumor Cell Line For The Study Of Epigenetic And Immunologic Treatments In Pancreatic Neuroendocrine Tumors:
Abstract selected for a Full Oral Presentation at the ACS Clinical Congress, October 19-22, 2024, San Francisco, CA. - Clinicopathologic Trends In Adrenocortical Carcinoma Over A Recent Decade: Abstract selected for an in-person e-poster presentation at the ACS Clinical Congress, October 19-22, 2024, San Francisco, CA.
- Saleh Z, Verchio V, Ghanem YK, Lou J, Hundley E, Rouhi AD, Joshi H, Moccia MC, Scalia DM, Lenart AM, Ladd Z, Minakata K, Shersher DD. Optimizing outcomes in paraesophageal hernia repair: a novel critical view. Surg Endosc. 2024;38(9):5385-5393. doi:10.1007/s00464-024-11104-2.
- Zena Saleh, Matthew C. Moccia, Zachary Ladd, Upasana Joneja, Yahui Li, Francis Spitz, Young Ki Hong, and Tao Gao. Pancreatic Neuroendocrine Tumors: Signaling Pathways and Epigenetic Regulation. Int. J. Mol. Sci. 2024, 25, 1331. https://doi.org/10.3390/ijms25021331.
- DNA-hypomethylating agent decitabine combined with captem chemotherapy induces reactivation of tumor suppressor genes via downregulation of dnmt1 expression in stc-1 neuroendocrine tumor cells, Poster, Moccia, Matthew, 3rd place winner at the Camden Scholars' Forum 2024, May 2, 2024
- Development Of A Bioluminescent Murine Neuroendocrine Tumor Cell Line For The Study Of Epigenetic And Immunologic Treatments In Pancreatic Neuroendocrine Tumors:
- Zena Saleh, MD (General Surgery Resident)
- Interplay Between Epigenetics And Immune Modulation In Pancreatic Neuroendocrine Tumor (PNET):
Abstract selected for a Quick Shot Presentation at the ACS Clinical Congress, October 19-22, 2024, San Francisco, CA. - Treatment Patterns For Pancreatic Cancer In Octogenarians: A National Cancer Database (NCDB) Study:
Abstract selected for an in-person e-poster presentation at the ACS Clinical Congress, October 19-22, 2024, San Francisco, CA. - Zena Saleh, Matthew C. Moccia, Zachary Ladd, Upasana Joneja, Yahui Li, Francis Spitz, Young Ki Hong, and Tao Gao. Pancreatic Neuroendocrine Tumors: Signaling Pathways and Epigenetic Regulation. Int. J. Mol. Sci. 2024, 25, 1331. https://doi.org/10.3390/ijms25021331.
- Saleh Z, Verchio V, Ghanem YK, Lou J, Hundley E, Rouhi AD, Joshi H, Moccia MC, Scalia DM, Lenart AM, Ladd Z, Minakata K, Shersher DD. Optimizing outcomes in paraesophageal hernia repair: a novel critical view. Surg Endosc. 2024;38(9):5385-5393. doi:10.1007/s00464-024-11104-2.
- Interplay Between Epigenetics And Immune Modulation In Pancreatic Neuroendocrine Tumor (PNET):
- Helen Toma, MD (GynOnc Fellow)
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NRF2 levels in high grade serous ovarian cancer: characterization and treatment, Helen Toma. Abstract accepted for poster presentation at the Molecular Analysis for Precision Oncology Congress (MAP) 2024, October 16-18, 2024, London, UK.
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Chemoresistance in high grade serous ovarian cancer molecular subtypes and the role of NRF2, Helen Toma. Abstract accepted for online publication at the American Society of Clinical Oncology Annual Meeting 2024, posted at 5:00 p.m. on May 23, 2024. Abstract Number for Publication: e17574
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- Zachary Ladd, MS (M2 Student)
- Triamterene and Asinex 1 inhibit NRF2 expression in NRF2MUT esophageal squamous cell carcinoma. Abstract selected by the SSAT Scientific Program Committee for a Quick Shot Lecture, Digestive Disease Week 2024, May 18-21, 2024, Washington, DC.
- Zena Saleh, Matthew C. Moccia, Zachary Ladd, Upasana Joneja, Yahui Li, Francis Spitz, Young Ki Hong, and Tao Gao. Pancreatic Neuroendocrine Tumors: Signaling Pathways and Epigenetic Regulation. Int. J. Mol. Sci. 2024, 25, 1331. https://doi.org/10.3390/ijms25021331.
- Marchuk H, Wang Y, Ladd ZA, Chen X, Zhang GF. Pathophysiological mechanisms of complications associated with propionic acidemia. Pharmacol Ther. 2023 Sep;249:108501.
July 2022 to June 2023
- Olivia Coburn-Flynn, MD (General Surgery Resident)
- Knapp K, Verchio V, Coburn-Flynn O, Li Y, Xiong Z, Morrison JC, Shersher DD, Spitz F, Chen X. Exploring cell competition for the prevention and therapy of esophageal squamous cell carcinoma. Biochem Pharmacol. 2023 Aug;214:115639.
- Knapp K, Verchio V, Coburn-Flynn O, Li Y, Xiong Z, Morrison JC, Shersher DD, Spitz F, Chen X. Exploring cell competition for the prevention and therapy of esophageal squamous cell carcinoma. Biochem Pharmacol. 2023 Aug;214:115639.
- Kristen Knapp, MD (General Surgery Resident)
- Shersher, David, Knapp, Kristen, Spitz, Francis, Lin, Andrew, Verchio, Vincent, Jupiter Andreis Antonelli, Zhang, Ping, Delong, Drew, Barroeta, Julieta, Chen, Xiaoxin, Zilberman, Brian. Adipose-Derived Stem Cells Prevent Anastomotic Leak: A Porcine Ischemic Esophagectomy Model. Journal of Surgical Research, 2025-01-01, Volume 305, Pages 65-79, Copyright © 2024 Elsevier Inc. https://doi.org/10.1016/j.jss.2024.10.054.
- Knapp K, Verchio V, Coburn-Flynn O, Li Y, Xiong Z, Morrison JC, Shersher DD, Spitz F, Chen X. Exploring cell competition for the prevention and therapy of esophageal squamous cell carcinoma. Biochem Pharmacol. 2023 Aug;214:115639.
- Vincent Verchio, MD (General Surgery Resident)
- Saleh Z, Verchio V, Ghanem YK, Lou J, Hundley E, Rouhi AD, Joshi H, Moccia MC, Scalia DM, Lenart AM, Ladd Z, Minakata K, Shersher DD. Optimizing outcomes in paraesophageal hernia repair: a novel critical view. Surg Endosc. 2024;38(9):5385-5393. doi:10.1007/s00464-024-11104-2.
- Shersher, David, Knapp, Kristen, Spitz, Francis, Lin, Andrew, Verchio, Vincent, Jupiter Andreis Antonelli, Zhang, Ping, Delong, Drew, Barroeta, Julieta, Chen, Xiaoxin, Zilberman, Brian. Adipose-Derived Stem Cells Prevent Anastomotic Leak: A Porcine Ischemic Esophagectomy Model. Journal of Surgical Research, 2025-01-01, Volume 305, Pages 65-79, Copyright © 2024 Elsevier Inc. https://doi.org/10.1016/j.jss.2024.10.054.
- Knapp K, Verchio V, Coburn-Flynn O, Li Y, Xiong Z, Morrison JC, Shersher DD, Spitz F, Chen X. Exploring cell competition for the prevention and therapy of esophageal squamous cell carcinoma. Biochem Pharmacol. 2023 Aug;214:115639.
- Rebecca Kelly, MD (GynOnc fellow)
- Kelly R, Aviles D, Krisulevicz C, Hunter K, Krill L, Warshal D, Ostrovsky O. The Effects of Natural Epigenetic Therapies in 3D Ovarian Cancer and Patient-Derived Tumor Explants: New Avenues in Regulating the Cancer Secretome. Biomolecules. 2023 Jul 1;13(7):1066.
- Kelly R, Aviles D, Krisulevicz C, Hunter K, Krill L, Warshal D, Ostrovsky O. The Effects of Natural Epigenetic Therapies in 3D Ovarian Cancer and Patient-Derived Tumor Explants: New Avenues in Regulating the Cancer Secretome. Biomolecules. 2023 Jul 1;13(7):1066.
- Zachary Ladd, BS (M1 Student)
- Arnold Rojas, BS (M1 Student)