Recent Resident Publications

Topper GV, Coleman JR. Sex-based differences in pathophysiology and outcomes in traumatic life-threatening bleeding. Damage Control Resuscitation: Identification and Treatment of Life-Threatening Hemorrhage. Book chapter. 2026.

Toomey NT, Thomas TE, Hall EJ, Nagaswami C, Alferiev I, Chen JM, Ferrari G, Stachelek SJ, Levy RJ. Vitamin B-6 pretreated bovine pericardial bioprosthetic heart valve leaflets demonstrate reduced platelet adhesion and activation. (2026) J Biomed Mater Res A. 

Plumb J, Topper GV, Metheny J, Morris P, Hess T, Hunter K, Voytik M, Magura C, Ratnasekera A, Egodage T. Surgical Stabilization of Rib Fractures in Geriatric Trauma Patients: A National Trauma Data Bank Review. Journal of the American Geriatric Society (2026).

Hamad S, Joshi H, Hess T, Jefferys S, Saleh Z, Sellers R, Zhu G, Shrank T, Moore R, Corcoran D, Simon J, Spitz F, Shersher D, Major M, Weissman B. Activating NRF2E79Q mutation alters the differentiation of human non-small cell lung cancer. Res Sq [Preprint]. 2025 May 15:rs.3.rs-6606334. doi: 10.21203/rs.3.rs-6606334/v1. Update in: Cancer Gene Ther. 2025 Dec;32(12):1428-1438. doi: 10.1038/s41417-025-00966-w. PMID: 40470216; PMCID: PMC12136215.

Hancin, E., Thange, L. & Goldenberg-Sandau, A. (2025) Emotional Resilience and Mental Health Support for Surgeon Leaders: Strategies to Prevent Burnout and Promote Well-Being Among Surgeons. Current Trauma Reports, 11(17). https://doi.org/10.1007/s40719-025-00290-6 

Sofield H, Giugliano DN. Passing the General Surgery Oral Board Exam. Book chapter. 2025. DOI: 10.1007/978-3-031-78244-2_28.

Morris P, Topper GV, Metheny J, Plumb J, Ratnasekera A, Anand T, Voytik M, Hess T, Nation RJ, Sofield H, Hunter K, Egodage T. Use of Whole Blood in Trauma Patients on Anticoagulation or Antiplatelet Therapy. Journal of Surgical Research (2025). 15;317:305-312. doi: 10.1016/j.jss.2025.11.033. PMID: 41401672.

Perea LL, Fletcher KL, Morgan ME, McNickle AG, Fraser D, Rosenthal M, Wang E, Goldenberg A, Hancin E, et al. (2025). Moderate to High-Grade Blunt Liver and Spleen Injuries Warrant Repeat Imaging to Identify Treatable Complications: Results of the Radiographic Evaluation of Delayed Solid Organ Complications (REDSOC) EAST Multicenter Trial. Annals of Surgery. DOI: 10.1097/SLA.0000000000006831

Catalano MA, Shin M, Toubat O, Rastogi R, Beqaj H, Smood BF, Toomey N, Edelson JB, Rossano J, O’Connor MJ, Ahmed H, Gaynor JW, Maeda K, Mavroudis CD. Listing for Pediatric Donation After Circulatory Death Heart Transplantation is Associated with Improved Waitlist Times. J Am Heart Assoc. 2025 Oct 9:e041633

Hamad SH, Joshi H, Hess T, Jefferys SR, Saleh Z, Bendjilali N, Sellers RS, Zhu G, Shrank T, Moore RT, Corcoran D, Simon JM, Spitz FR, Shersher D, Major MB, Weissman BE. Activating NRF2E79Q mutation alters the differentiation of human non-small cell lung cancer. Cancer Gene Ther. 2025 Dec;32(12):1428-1438. doi: 10.1038/s41417-025-00966-w. Epub 2025 Oct 11. PMID: 41076449; PMCID: PMC12690292.

Topper GV, Bamimore M, Hess T, Metheny J, Morris P, Plumb J, Valeri A, Hunter K, Mossop Corey, Egodage T. A Single-Center Review of Renal Replacement Therapy in Patients With Acute Traumatic Brain Injury. Cureus (2025). 10.7759/cureus.100279

Toomey NT, Shersher DD. A Warning Sign or Rescue Flare? New Insights on Sarcopenia in Early-Stage Non-Small Lung Cancer. J Am Coll Surg. 2025 Aug 1;241(2):280-281

Lombardo J, Florea IB, Toomey N, Khirzman P, Shersher DD. The Landmark Series: Role of Curative Intent Treatment for Oligometastatic Disease of the Lung. Ann Surg Oncol. 2025 July 17

Kim S, Majumdar A, Waters JP, Topper GV, Ghanem Y, Elbezanti W, Song S, Hong YK. Immunoresistant to immunosensitive - Histotripsy's unique potential to overcome resistance. Critical Reviews in Oncology/Hematology (2025). 27;217:105054. doi: 10.1016/j.critrevonc.2025.105054. PMID: 41317817.

Chopra A, Nitsche L, Toomey N, Maeda K, Mavroudis C. Use of right axillary thoracotomy approach for minimally invasive tricuspid valve repair in the setting of paediatric infective endocarditis. Cardiology in the Young. 2025;35(9):1956-1958.

Topper GV, Waters JP, Morris P, Coleman JR. Uncovering sex-based disparities in trauma surgery research. Journal of Trauma & Acute Care Surgery (2025).doi: 10.1097/TA.0000000000004822. PMID: 41196224.

Ghanem YK, Nation R, Sofield H, Rouhi AD, Gandhi SV, Sier R, Saleh Z, Joshi ART, Patel R. DAX Copilot: ambient AI scribe may help reduce surgical resident clinical documentation burden. Surg Endosc. 2025 Dec 9. doi: 10.1007/s00464-025-12404-x. Epub ahead of print. PMID: 41366572.

Saleh Z, Nation RJ, Moccia MC, Kalola A, Ghanem Y, Joshi H, Joneja U, Li Y, Spitz F, Gao T, Hong YK. DNA methyltransferase 1 correlates with immune modulation in pancreatic neuroendocrine tumors. Sci Rep. 2025 Nov 24;15(1):41497. doi: 10.1038/s41598-025-25384-8. PMID: 41286274; PMCID: PMC12644564.

Saleh Z, Toomey NT, Kumar A, Wang H, Harbus T, Cook G, Shersher D, Rosenbloom M, Minakata K. Successful Replication of the Transconal Repair Technique for Anomalous Aortic Origin of the Left Main Coronary Artery. JACC Case Rep. 2025 Nov 28:106134. doi: 10.1016/j.jaccas.2025.106134. Epub ahead of print. PMID: 41313292.

Sofield H, Buchnerb SH, Nation RJ, Hess T, Topper GV, Moccia MC, McClane SJ, Giugliano DN, Spitz FR, Hong YK. Treatment Patterns of Anal Melanoma in the Era of Immunotherapy. American Journal of Surgery (2025). PMID: 41108887 DOI: 10.1016/j.amjsurg.2025.116658

Topper GV, Egodage T, Fox N. Low Radiation, High Yield: Reclaiming the First-Line Role of Radiographs. Journal of Trauma and Acute Care Open (2025). PMID: 40761846. DOI: 10.1136/tsaco-2025-002003. 

Harris M, Bolaji T, DiStefano S, Subedi K, Getchell J, Knapp K, Sheth A, Egodage T, Faizi Z, Morales J, Seng SS, Hlopak J, Parthiban V, Batool A, Kaufman EJ, Ratnasekera AM. Role of preoperative CT imaging in penetrating thoraco-abdominal injuries: A multicenter study of urban trauma centers. Am J Surg. 2025 Jan;239:116032. doi: 10.1016/j.amjsurg.2024.116032. Epub 2024 Oct 19. PMID: 39471731; PMCID: PMC11649440.

Nation RJ, Topper GV, Egodage T. Rethinking Routine: Selective Postoperative Lab Testing is Safe in Emergency Surgery Patients. Journal of Trauma and Acute Care Open (2024). PMID: 39845990. DOI: 10.1136/tsaco-2024-001714. 

Williams J, Joshi H, Schwartz M, Kalola A, Mercado A, Saracco B, Adams A, Chaaya A, Baik D, Elfant A, Hong YK. Endoscopic repair of duodenal perforations, a scoping review. Surg Endosc. 2024 Sep;38(9):4839-4845. doi: 10.1007/s00464-024-11133-x. Epub 2024 Aug 14. PMID: 39143329; PMCID: PMC11362252.

Sandilos G, Butchy MV, Koneru M, Gongalla S, Sensenig R, Hong YK. Histotripsy - hype or hope? Review of innovation and future implications. J Gastrointest Surg. 2024 Aug;28(8):1370-1375. doi: 10.1016/j.gassur.2024.05.038. Epub 2024 Jun 9. PMID: 38862075.

Lou J, Kooragayala K, Williams J, Kalola A, Crudeli C, Sandilos G, Butchy MV, Shersher DD, Burg JM. Diagnostic Workup and Therapeutic Intervention of Hiatal Hernias Discovered as Incidental Findings on Computed Tomography. Am Surg. 2024 Jun;90(6):1357-1364. doi: 10.1177/00031348241230096. Epub 2024 Jan 27. PMID: 38279933.

Moccia MC, Waters JP, Dibato J, Ghanem YK, Joshi H, Saleh ZB, Toma H, Giugliano DN, McClane SJ. The contribution of household income to rectal cancer patient characteristics, treatment, and outcomes from 2010 to 2020. Heliyon. 2024 Jun 22;10(13):e33318. doi: 10.1016/j.heliyon.2024.e33318. PMID: 39040277; PMCID: PMC11261109.

Kooragayala K, Joshi H, Goodwin B, Spitz FR, Hong YK. Impact of hybrid work on healthcare provider burnout in surgery. Am J Surg. 2024 May;231:137-139. doi: 10.1016/j.amjsurg.2023.12.020. Epub 2023 Dec 20. PMID: 38143214.

Rouhi AD, Ghanem YK, Yolchieva L, Saleh Z, Joshi H, Moccia MC, Suarez-Pierre A, Han JJ. Can Artificial Intelligence Improve the Readability of Patient Education Materials on Aortic Stenosis? A Pilot Study. Cardiol Ther. 2024 Mar;13(1):137-147. doi: 10.1007/s40119-023-00347-0. Epub 2024 Jan 9. PMID: 38194058; PMCID: PMC10899139.

Saleh, Z., Verchio, V., Ghanem, Y. K., Lou, J., Hundley, E., Rouhi, A. D., Joshi, H., Moccia, M. C., Scalia, D. M., Lenart, A. M., Ladd, Z. A., Minakata, K., & Shersher, D. D. (2024). Optimizing outcomes in paraesophageal hernia repair: a novel critical view. Surgical endoscopy, 38(9), 5385–5393. https://doi.org/10.1007/s00464-024-11104-2

Conrad-Schnetz, K., Anand, R.J., Relles, D. Hilt, E.K., Ghanem, Y.K., Joshi, A. Determination of Quality in Training Programs Based on Outcomes and Data. Curr Surg Rep 12, 138–145 (2024). https://doi.org/10.1007/s40137-024-00400-4 

Ghanem YK, Rouhi AD, Al-Houssan A, Saleh Z, Moccia MC, Joshi H, Dumon KR, Hong Y, Spitz F, Joshi AR, Kwiatt M. Dr. Google to Dr. ChatGPT: assessing the content and quality of artificial intelligence-generated medical information on appendicitis. Surg Endosc. 2024 May;38(5):2887-2893. doi: 10.1007/s00464-024-10739-5. Epub 2024 Mar 5. PMID: 38443499; PMCID: PMC11078845.

Toomey NT, Lounsbury C, Mahmoud O, Yaranov DM, Craig JM. A novel technique for achieving optimal pump position when implanting the Heartmate 3 via lateral approach. JTCVS Tech, 2024; 27:129-131.

Rouhi, A. D., Choudhury, R. A., Hoeltzel, G. D., Ghanem, Y. K., Bababekov, Y. J., Suarez-Pierre, A., Yule, A., Vigneshwar, N. G., Williams, N. N., Dumon, K. R., & Nydam, T. L. (2024). Ventricular Remodeling Following Metabolic and Bariatric Surgery Decreases Need for Heart Transplantation: A Predictive Model. Obesity surgery, 34(1), 15–21. https://doi.org/10.1007/s11695-023-06948-x 

Saleh Z, Moccia MC, Ladd Z, Joneja U, Li Y, Spitz F, Hong YK, Gao T. Pancreatic Neuroendocrine Tumors: Signaling Pathways and Epigenetic Regulation. Int J Mol Sci. 2024 Jan 22;25(2):1331. doi: 10.3390/ijms25021331. PMID: 38279330; PMCID: PMC10816436.

Knapp K, Verchio V, Coburn-Flynn O, Li Y, Xiong Z, Morrison JC, Shersher DD, Spitz F, Chen X. Exploring cell competition for the prevention and therapy of esophageal squamous cell carcinoma. Biochem Pharmacol. 2023 Aug;214:115639. doi: 10.1016/j.bcp.2023.115639. Epub 2023 Jun 7. PMID: 37290594; PMCID: PMC10528900.

Clark A, McMackin KK, Knapp K, Zemela M, Tjaden B Jr, Batista P, Carpenter JP, Lombardi JV. Surveillance duplex ultrasound prompted interventions after carotid endarterectomy. J Vasc Surg. 2024 Feb;79(2):280-286. doi: 10.1016/j.jvs.2023.10.001. Epub 2023 Oct 5. PMID: 37804953.

Sandilos G, Menger A, Kooragayala K, Zhu C, Daneshpooy S, Gefen R, Kovacs J, Giugliano DN, Kwiatt ME, McClane SJ. Diagnostic accuracy of endoscopy in determining rectal tumor proximity to the peritoneal reflection. Int J Colorectal Dis. 2023 Apr 25;38(1):109. doi: 10.1007/s00384-023-04392-y. PMID: 37097459.

Toomey NT, Dono A, Lounsbury C, Byerly S, Criag J, DeCampli, W, Lenart E. Persistent hypoxia after blunt thoracic trauma due to flail tricuspid valve leaflet and patent foramen ovale. The American Surgeon. 2023;89(11):4992-4995.

Kooragayala K, Lou J, Butchy V, Balakrishnan A, Sandilos G, Kwiatt M, Giugliano D, McClane S. Impact of Frailty on Patient Outcomes after Hartmann's Reversal: A NSQIP Analysis. Am Surg. 2023 Dec;89(12):5459-5465. doi: 10.1177/00031348231156785. Epub 2023 Feb 14. PMID: 36787880.

Bhat V, Koneru M, Knapp K, Joneja U, Morrison J, Hong YK. Identification and Treatment of SMARCA4 Deficient Poorly Differentiated Gastric Carcinoma. Am Surg. 2023 Nov;89(11):4987-4989. doi: 10.1177/00031348221146972. Epub 2022 Dec 19. PMID: 36533880.

Rouhi, A. D., Han, J. J., Ghanem, Y. K., Pervaiz, S. S., Suarez-Pierre, A., Choudhury, R. A., Bermudez, C. A., Williams, N. N., & Dumon, K. R. (2023). Quality and readability of online patient information on the left ventricular assist device. Artificial organs, 47(6), 1029–1037. https://doi.org/10.1111/aor.14479 

Rouhi, A. D., Ghanem, Y. K., Hoeltzel, G. D., Miura, J. T., Aarons, C. B., Williams, N. N., Dumon, K. R., & Karakousis, G. C. (2023). Quality and readability assessment of online patient information on cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Journal of surgical oncology, 127(4), 699–705. https://doi.org/10.1002/jso.27143 

Batchu S, Hakim A, Henry OS, Madzo J, Atabek U, Spitz FR, Hong YK. Transcriptome-guided resolution of tumor microenvironment interactions in pheochromocytoma and paraganglioma subtypes. J Endocrinol Invest. 2022 May;45(5):989-998. doi: 10.1007/s40618-021-01729-8. Epub 2022 Jan 28. PMID:35088383.

Miller H, Bush K, Delancy M, De Leo N, Joshi H, Saracco B, Adams A, Gaughan J, Bonawitz S. Effect of preoperative radiation on free flap outcomes for head and neck reconstruction: An updated systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2022 Feb;75(2):743-752. doi: 10.1016/j.bjps.2021.09.050. Epub 2021 Oct 23. PMID: 34810143.

Brajcich BC, Platoff RM, Thompson VM, Hall B, Ko CY, Pitt HA. Hyperamylasemia grade versus drain fluid amylase: which better predicts pancreatectomy outcomes? PB (Oxford). 2022 Jan 3:S1365-182X(21)01743-3. doi: 10.1016/j.hpb.2021.12.017. Epub ahead of print. PMID: 35034836

Platoff RM, Lou J, Bush K, Zhu C, Spitz E, Gaughan JP, Atabek U, Spitz F, Hong YK. Gastric Neuroendocrine Tumor Treatment and Survival Outcome Depends on Facility Type. Am Surg. 2022 Jun 19:31348221109460. doi: 10.1177/00031348221109460. Online ahead of print.

Sandilos G, Zhu C, Giugliano DN, Kwiatt M, Wang YR, Hunter K, McClane SJ. Risk Factors Associated with the Development of Colorectal Anastomotic Strictures Prior to Diverting Loop Ileostomy Reversal. Am Surg. 2022 Jan 22:31348221075785. doi: 10.1177/00031348221075785. Epub ahead of print. PMID: 35068200.

Crudeli C, Zilberman B, Williams J, Burg J, Shersher D. COVID-19's impact on lung tissue: A case report. Int J Surg Case Rep. 2022 Mar;92:106905. doi:10.1016/j.ijscr.2022.106905. Epub 2022 Mar 1. PMID: 35251905; PMCID: PMC8886685.

Zilberman B, Kooragayala K, Lou J, Ghobrial G, De Leo N, Emery R, Ostrovsky O, Zhang P, Platoff R, Zhu C, Hunter K, Delong D, Hong Y, Brown SA, Carpenter JP. Treatment of Abdominal Aortic Aneurysm Utilizing Adipose-Derived Mesenchymal Stem Cells in a Porcine Model.  J Surg Res. 2022 May 25;278:247-256. doi: 10.1016/j.jss.2022.04.064. Online ahead of print. 

Zhu C, Platoff R, Ghobrial G, Saddemi J, Evangelisti T, Bucher E, Saracco B, Adams A, Kripalani S, Atabek U, Spitz FR, Hong YK. What to do When Decompressive Gastrostomies and Jejunostomies are not Options? A Scoping Review of Transesophageal Gastrostomy Tubes for Advanced Malignancies. Ann Surg Oncol. 2022 Jan;29(1):262-271. doi: 10.1245/s10434-021-10667-x. Epub 2021 Sep 21. PMID:34546480.

Zhu C, Hong YK. ASO Author Reflections: Improving Quality of Life for Patients With Malignant Bowel Obstructions: A Role for Transesophageal Gastrostomy Tubes. Ann Surg Oncol. 2022 Jan;29(1):272-273. doi:10.1245/s10434-021-10816-2. Epub 2021 Sep 22. PMID: 34550477.

Zhu C, McCloskey D, Sandilos G, Zilberman B, Crudeli C, Hunter K, Mitchell T, Burg JM, Shersher DD. The State of Racial and Gender Diversity In Cardiothoracic Surgery Training. Ann Thorac Surg. 2022 Apr 6:S0003-4975(22)00482-9. doi: 10.1016/j.athoracsur.2022.02.083. Epub ahead of print. PMID: 35398039.

Zhu C, Sandilos G, Henry O, Sensenig R, Gaughan J, Spitz F, Atabek U, Hong Y. Medicaid expansion is associated with earlier diagnosis of gastric cancer. Am J Surg. 2022 Feb 5:S0002-9610(22)00061-7. doi: 10.1016/j.amjsurg.2022.02.002. Epub ahead of print. PMID: 35148884.

De Leo N, Melillo A, Zhang P, Badach J, Miller H, Lin A, Williamson J, Ghobrial G, Gaughan J, Krishnadoss V, Noshadi I, Brown SA, Carpenter JP. Development of a Model for Abdominal Aortic Aneurysms in Swine. J Surg Res. 2021 Dec;268:79-86. doi: 10.1016/j.jss.2021.05.047. Epub 2021 Jul 18. PMID: 34289418.

Linden K, Melillo A, Gaughan J, Obinero C, Kellish A, Wozniak MR, Patel RM, Pandya V, Atabek U, Spitz F, Hong YK. The Role of Neoadjuvant Versus Adjuvant Therapy for Duodenal Adenocarcinoma: A National Cancer Database Propensity Score Matched Analysis. Am Surg. 2021 Jul;87(7):1066-1073. doi:10.1177/0003134820954821. Epub 2020 Dec 9. PMID: 33291951.

McCloskey D, Linden K, Lin A, Zhang P, Schweinsburg J, Melillo A, Wang H, Barroeta J, Brown S, Carpenter J, Spitz F, Shersher D. Human Adipose Derived Stem Cells Enhance Healing in a Rat Model of Esophageal Injury with Stent. J Surg Res. 2021 Nov;267:458-466. doi: 10.1016/j.jss.2021.05.035. Epub 2021 Jul 7. PMID: 34243035.

Miller H, Bush KM, Betances A, Kota R, Wu S, De Leo N, Gaughan J, Bonawitz S. Effect of Daily Dosage of Morphine Milligram Equivalents on Free Flap Complications: A Single-Institution Retrospective Study. J Plast Reconstr Aesthet Surg. 2021 Oct;74(10):2486-2494. doi: 10.1016/j.bjps.2021.03.028. Epub 2021 Apr 8. PMID: 33935007.

Platoff R, Villalobos MA, Hagaman AR, Liu Y, Matthews M, DiSanto ME, Carpenter JP, Zhang P. Effects of radiation and chemotherapy on adipose stem cells: Implications for use in fat grafting in cancer patients. World J Stem Cells. 2021 Aug 26;13(8):1084-1093. doi: 10.4252/wjsc.v13.i8.1084. PMID:34567427; PMCID: PMC8422936.