Cooper Neurologic Institute is actively engaged in numerous clinical trials and ongoing studies. We highly encourage residents to participate in these research opportunities and provide ample resources for them to pursue projects aligned with their interests. Additionally, we maintain several registries and databases that residents and medical students can utilize to initiate retrospective studies. We take pride in our residents' achievements in publishing research during their residency and presenting their work at various national meetings.
Active clinical trials at Cooper Neurologic Institute
- A phase I, open-label, multi-center, pharmacokinetic, pharmacodynamic and safety study of tenectaplase in adult patients with acute ischemic stroke
- Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)
- Evaluation of Acute Mechanical Revascularization in Large Vessel Occlusion Stroke with Minor Symptoms (NIHSS<6) in Patients Last Seen Well < 24 Hours (MinOr Stroke Therapy Evaluation: MOSTE)
- A Multi-centre, Interventional, Post-marketing, Randomised, Double-blind, Crossover Study to Evaluate the Clinical Safety and Efficacy of AbobotulinumtoxinA in Comparison with OnabotulinumtoxinA when Treating Adults with Upper Limb Spasticity
- A Prospective, Randomized, Controlled, Interventional Clinical Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical MonoPoint Reperfusion System for Aspiration Embolectomy in Acute Ischemic Stroke Patients.
- Chronic Subdural Hematoma Treatment with Embolization Versus Surgery Study (CHESS)
- Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
- Long-Term Observational Extension of Participants in the CREST-2 Randomized Clinical Trial (C2LOE)
- A prospective, multi-center, open label and single arm clinical investigation to evaluate the safety and efficacy of using the Zoom Reperfusion System in thrombectomy procedures to treat acute ischemic stroke patients
Recent publications by residents
| 2024 |
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| Rissardo JP, Byroju VV, Mukkamalla S, Caprara ALF. A Narrative Review of Stroke of Cortical Hand Knob Area. Medicina (Kaunas). 2024 Feb 13;60(2):318. PMID: 38399606; PMCID: PMC10890039. |
| Liu TT, Frost ED, Donlon J, Gandhi RM, Mohammadi T, Murray BP, Shad MU, Koola MM. Surge of Midazolam Use in the Midst of Lorazepam Shortage. J Clin Psychopharmacol. 2023 Nov-Dec 01;43(6):520-526. PMID: 37930205. |
| Rissardo JP, Byroju VV, Mukkamalla S, Caprara ALF. A Narrative Review of Stroke of Cortical Hand Knob Area. Medicina (Kaunas). 2024 Feb 13;60(2):318. doi: 10.3390/medicina60020318. PMID: 38399606; PMCID: PMC10890039. |
| Mangold A, Frost E, Raddell T, Schoifet A, Wang Z. A Case of Life-Threatening Postpartum Necrotizing Pancreatitis Requiring Gastrocystostomy With Serial Pancreatic Necrosectomies. Cureus. 2024 Apr 7;16(4):e57779. PMID: 38716029; PMCID: PMC11074802. |
| 2023 |
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| Edwards C, Drumm B, Siegler JE, Schonewille WJ, Klein P, Huo X, Chen Y, Abdalkader M, Qureshi MM, Strbian D, Liu X, Hu W, Ji X, Li C, Fischer U, Nagel S, Puetz V, Michel P, Alemseged F, Sacco S, Yamagami H, Yaghi S, Strambo D, Kristoffersen ES, Sandset EC, Mikulik R, Tsivgoulis G, Masoud HE, de Sousa DA, Marto JP, Lobotesis K, Roi D, Berberich A, Demeestere J, Meinel TR, Rivera R, Poli S, Ton MD, Zhu Y, Li F, Sang H, Thomalla G, Parsons M, Campbell BCV, Zaidat OO, Chen HS, Field TS, Raymond J, Kaesmacher J, Nogueira RG, Jovin TG, Sun D, Liu R, Qureshi AI, Qiu Z, Miao Z, Banerjee S, Nguyen TN. Basilar artery occlusion management: Specialist perspectives from an international survey. J Neuroimaging. 2023 May-Jun;33(3):422-433. PMID: 36781295. |
| Mason Sharma A, Birnhak A, Sanborn E, Bhana N, Kazmi K, Thon JM, Thon OR, Siegler JE. Neuroimaging mimics of anoxic brain injury: A review. J Neuroimaging. 2023 Jul-Aug;33(4):467-476. PMID: 37070435. |
| Thon JM, Sharkus R, Thakkar R, Hunter K, Siegler JE, Thon OR. Utilization of FDA approved treatments for neuromyelitis optica spectrum disorder in clinical practice: A survey study of academic neuroimmunologists. Mult Scler Relat Disord. 2023 Dec;80:105076. PMID: 37866024. |
| Sharkus R, Thakkar R, Kolson DL, Constantinescu CS. Dimethyl Fumarate as Potential Treatment for Alzheimer's Disease: Rationale and Clinical Trial Design. Biomedicines. 2023 May 8;11(5):1387. PMID: 37239057; PMCID: PMC10216730. |
| Bhatti KS, Rajagopalan S. Case report: Invasive neuromonitoring in status epilepticus induced hypoxic ischemic brain injury. Front Neurol. 2023 Nov 30;14:1284098. PMID: 38099068; PMCID: PMC10720614. |
| Siegler JE, Dasgupta S, Abdalkader M, Penckofer M, Yaghi S, Nguyen TN. Cerebrovascular Disease in COVID-19. Viruses. 2023 Jul 21;15(7):1598. PMID: 37515284; PMCID: PMC10385090. |
| Frost ED, Donlon J, Mitwally A, Magnani G, Tomlin S, Berk M, Koola MM. Paper Charts: A Continued Barrier to Psychiatric Care in the Midst of a Broken and Fragmented Mental Health System. J Nerv Ment Dis. 2023 Jan 1;211(1):1-4. PMID: 36596285. |
| Pitton Rissardo J, Caprara ALF. Neuroimaging Techniques in Differentiating Parkinson's Disease from Drug-Induced Parkinsonism: A Comprehensive Review. Clin Pract. 2023 Nov 15;13(6):1427-1448. PMID: 37987429; PMCID: PMC10660852. |
| Pitton Rissardo J, Fornari Caprara AL. Cardiac 123I-Metaiodobenzylguanidine (MIBG) Scintigraphy in Parkinson's Disease: A Comprehensive Review. Brain Sci. 2023 Oct 18;13(10):1471. PMID: 37891838; PMCID: PMC10605004. |
| 2022 |
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| Dmytriw AA, Dibas M, Phan K, Efendizade A, Ospel J, Schirmer C, Settecase F, Heran MKS, Kühn AL, Puri AS, Menon BK, Sivakumar S, Mowla A, Vela-Duarte D, Linfante I, Dabus GC, Regenhardt RW, D'Amato S, Rosenthal JA, Zha A, Talukder N, Sheth SA, Hassan AE, Cooke DL, Leung LY, Malek AM, Voetsch B, Sehgal S, Wakhloo AK, Goyal M, Wu H, Cohen J, Ghozy S, Turkel-Parella D, Farooq Z, Vranic JE, Rabinov JD, Stapleton CJ, Minhas R, Velayudhan V, Chaudhry ZA, Xavier A, Bullrich MB, Pandey S, Sposato LA, Johnson SA, Gupta G, Khandelwal P, Ali L, Liebeskind DS, Farooqui M, Ortega-Gutierrez S, Nahab F, Jillella DV, Chen K, Aziz-Sultan MA, Abdalkader M, Kaliaev A, Nguyen TN, Haussen DC, Nogueira RG, Haq IU, Zaidat OO, Sanborn E, Leslie-Mazwi TM, Patel AB, Siegler JE, Tiwari A; North American Neurovascular COVID-19 (NAN-C) Consortium & Society of Vascular and Interventional Neurology (SVIN) Investigators. Acute ischemic stroke associated with SARS-CoV-2 infection in North America. J Neurol Neurosurg Psychiatry. 2022 Apr;93(4):360-368. PMID: 35078916. |
| Zhang L, Kamen S, Niles J, Goss J, Heslin ME, Vigilante N, Thau L, Edwards C, Marden KR, Thon JM, Yeager T, Siegler JE. Resident-Driven Dysphagia Screening Protocol for Expedited Antithrombotic Delivery in Acute Ischemic Stroke. Neurohospitalist. 2022 Jul;12(3):467-475. PMID: 35755228; PMCID: PMC9214955. |
| DePolo D, Gillen S, Marden K, Rajagopalan S, Thon OR, Siegler JE, Thon JM. Severe Wernicke's Encephalopathy Associated with Cortical Ribboning and Intracranial Hemorrhage. Neurohospitalist. 2022 Oct;12(4):702-705. PMID: 36147752; PMCID: PMC9485700. |